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Operations Chemist

Job Title: Operations Chemist
Contract Type: Permanent
Location: Alnwick
Salary: Competitive salary + shift allowance
Contact Name: Matthew Rollinson
Contact Email:
Job Published: July 02, 2019 09:46

Job Description

Operations Chemist

Up to £28,000

Permanent role

Based in Alnwick


We are recruiting for an expanding client in the North East for an Operations Chemist to perform and manage chemical syntheses in accordance with regulatory and company procedures.


This role will support scale up and manufacturing phases of product development including the provision of shift cover as required.  In-process analysis, including sample preparation and interpretation.  Use test of critical raw materials and intermediates.  Participation in and preparation of HAZOP and risk assessments. 


You will have the opportunity to work on a variety of pharmaceutical projects covering a range of synthetic organic chemistry. Our client is based in an excellent part of the country for relocation, and on a fantastic facility with great resources and equipment, they are conveniently accessible from many surrounding towns and villages in the Alnwick area. 


  • Perform syntheses and purifications of various chemical entities within agreed timeframes. Maintain Laboratory Notebooks of Batch Synthesis Instructions, prepare Analytical Data Sheets and reports.   
  • Manufacture API at the tens of grams to tens of kilogram scale.  Provide manufacturing shift cover as required.
  • Apply the skills highlighted above to the manufacture of non-pharmaceutical materials, impurities and degradation products at the tens of grams to tens of kilogram scale. 
  • Perform in-process analytical testing where relevant and/or ensure that analytical, microbiological (where relevant) and materials science/spectroscopic testing needs are discussed and agreed with the CMC team.
  • Contribute to laboratory operations, equipment acquisition and maintenance, contracts, housekeeping, stock control, disposals and liaise with other departments dealing with such matters. 
  • Ensure, where required, that laboratory work and associated documentation complies with GMP or other regulatory requirements, internal policies/procedures and client requirements,
  • Work with due regard to health &safety of self and others.
  • Work flexibly across the site to meet business needs.


Your background:


You will have a good knowledge and experience of synthetic chemistry covering process optimisation to ensure successful and cost-effective scale-up. Good understanding of process safety and hazard operability. Proficiency in carrying out kilo-scale chemical processing. Awareness of the current regulatory environment, a comprehensive understanding of process analytical chemistry, impurity control and/or sufficient analytical skills to conduct in-process testing and a good understanding of the factors controlling API physical form. Good written and oral communication skills.  


Either a degree level (or equivalent) qualification in Chemistry (BSc or MSc / MChem are encouraged to apply) or a closely related discipline or a completed apprenticeship as a chemical operator, with minimum of one year’s relevant industrial experience. 


On this occasion, LiCa Scientific is acting as an employment agency.