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Flow Chemist

Posted 27 days ago

Location Alnwick Job Type Permanent
Salary c£35,000 + package Sector Synthesis Chemistry

Flow Chemist

 

Based in Alnwick

 

Salary £25,000 to £35,000

 

Permanent role

 

We are working with a client in the North East who are hiring for a Flow Chemist to join their team. They are an expanding organisation specialising in radiochemistry, and this role will help drive their research into this field of synthesis.

 

What you’ll do:

 

This role will see you working in the Drug Substance / Technology team and manufacturing multi-kilogram quantities of high value GMP and/or non-GMP drug substances and intermediates to support the pharmaceutical development pipeline.


Successful applications of process intensification and continuous manufacturing technology (‘Flow Chemistry’) at our client over the past three years has led to the creation of a three-year technology development project in academic collaboration with a Russell Group University.

 

This is an exciting project that aims to combine data driven process development with process modelling to inform the design and build of a flexible, modular manufacturing unit capable of producing up to 100kg of high value products.

 

The following are the core responsibilities of the role:

 

  • You will be responsible for development, implementation and optimisation of Flow Chemistry solutions to ensure the design of robust, sustainable and efficient chemical manufacturing processes.
  • You will be expected to participate in the evaluation of alternative routes to our clients’ targets to identify steps for application of continuous manufacturing approaches. They will use lab based experimental data to build early stage, fit for purpose, process models and use these to guide further rounds of experimental data to support decisions on equipment selection for scale up.
  • The position reports to the project technical leader and will work closely with the wider chemistry team as well as academic researchers involved with the prototyping of novel reactors.
  • Critical tasks involve enabling new chemical transformations and influencing route design. The individual will support API campaigns at lab and kilo-lab scales from a few 100s grams to 100s of kilos.

 

Your background:

 

We are seeking PhD in flow chemistry or organic chemistry with additional post-doctoral or industrial experience, in practical applications of flow chemistry. We are seeking someone who is keen to expand their knowledge in this field and with a curiosity to develop this technology field at our client.

 

On this occasion, LiCa Scientific is acting as an employment agency.

 

 

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